Allies and friends,

Last week, we wrote to you about the Final Cass Review being published. This week, we want to provide you with a summary analysis of that Review from the Society for Gender Based Medicine (SEGM).

More and more studies are revealing that transgender interventions are not built on a firm medical foundation or scientific basis. A February 2024 Dutch study found that most gender-confused kids grow out of their desire to change sex. A March 2024 Mayo Clinic study found that puberty blockers may not be reversible and could raise children’s risk of fertility problems and cancer. All of these are linked below.


The Biological Integrity Team
The American College of Pediatricians

SEGM Provides Analysis of the Final Cass Review

The Society for Gender Based Medicine (SEGM) has provided a summary analysis of the Final Cass Review. They noted that for England, the Cass Report marks the end of the era of a highly medicalized approach to the treatment of young people with gender-related distress, which has come to be known as “gender-affirming care.”

Read the SEGM analysis here.

Dutch Study: Most Gender-Confused Kids Grow Out of their Desire to Change Sex

Researchers in the Netherlands tracked more than 2,700 children from age 11 to their mid-twenties, asking them every three years of feelings about their gender. The researchers concluded in this study published at the end of February 2024:

“Individuals with an increasing gender non-contentedness more often were female and both an increasing and decreasing trajectory were associated with a lower global self-worth, more behavioral and emotional problems, and a non-heterosexual sexual orientation.

Gender non-contentedness , while being relatively common during early adolescence, in general decreases with age and appears to be associated with a poorer self-concept and mental health throughout development.”

Read an article on the Dutch study here.

Read the study here.

Mayo Clinic Study: Puberty Blockers May Not Be Reversible and Could Raise Children’s Risk of Fertility Problems and Cancer

A study published in March 2024 by the Mayo Clinic concluded that puberty blockers may not be reversible and could raise children’s risk of fertility problems and cancer.

One of the authors of the study, the geneticist, Nagarajan Kannan, said, “At the tissue level, we report mild-to-severe sex gland atrophy in puberty blocker-treated children.”

They concluded, “We provide unprecedented histological evidence revealing detrimental pediatric testicular sex gland responses’ to the drugs.”

Read an article about the Mayo study here.

Read the study here.